The 4400 is the hit USA show about a group of 4400 people that were abducted over the course of 50 years. They all return on the same day to Seattle, Washington. None of them have aged a day and they can't remember where they've been. The 4400 begin to develop superhuman abilities. The show follows Tom Baldwin and Diana Skouris, two agents from the National Threat Assessment Command (NTAC), who are assigned to deal with the newly returned 4400. Throughout the course of the show, we discover why the 4400 were abducted, why they were returned, and how their presence will stop a major catastrophe. Each week, the 4400 and NTAC face obstacles, including government conspiracies, murder, terrorist factions like the Nova Group, and the mysterious Isabelle Tyler. The battle ranges over Promicin, the neurotransmitter that gives them their power.