You, Me and Dupree is a comedy film released on July 14, 2006. It is directed by Anthony Russo and Joe Russo, written by Mike LeSieur, and produced by Mary Parent, Scott Stuber, and Owen Wilson.

The film revolves around newlyweds Carl and Molly Peterson (Matt Dillon and Kate Hudson), inviting the best man of their wedding, Randolph Dupree (Wilson), to move in with them, after he has lost his job and apartment. But Dupree inevitably overstays his welcome.

• Tagline: Two's company. Dupree's a crowd.