The American version of the game show The Weakest Link aired on NBC from April 16, 2001 to July 14, 2002. Ten episodes were left unaired until appearing on PAX in 2002, with the remainder eventually airing on GSN. An accompanying daily syndicated series premiered on January 7, 2002 and ran until May 20, 2003.

PAX also briefly ran reruns of both the NBC and syndicated series. GSN currently has the rights to both series, although neither currently appear on the network's schedule. On November 1, 2009 GSN resumed airing reruns of the show, airing early Sunday mornings.

Hosts and announcers

Like the British version, Anne Robinson served as host for the NBC Weakest Link. George Gray, whose most notable hosting experience to that point had been on Extreme Gong, hosted the syndicated version.