Throw Momma from the Train is a comedy film released in 1987. The movie was inspired by the 1951 Alfred Hitchcock thriller Strangers on a Train, which also plays a role in the movie. The title comes from the 1956 hit song, Mama From The Train (A Kiss, A Kiss) written by Irving Gordon and sung by Patti Page.

It stars Billy Crystal, Danny DeVito (who also directed), Anne Ramsey, Kim Greist, Rob Reiner, Branford Marsalis, and Kate Mulgrew, with cameos from Rob Reiner and Oprah Winfrey.