Shirley Ann Manson (born 26 August 1966) is a Scottish musician, actress, and the lead vocalist of the band Garbage.

She began her career in Edinburgh in the early 1980s, most notably performing backing vocals and keyboards for local band Goodbye Mr. Mackenzie before fronting side-project Angelfish while signed as a solo artist. Having seen Manson in an Angelfish video on MTV, Garbage invited Manson to record with them as the band's lead singer.153 F.Supp.2d 462 RADIOACTIVE, J.V., Plaintiff, v. Shirley MANSON, Defendant. No. 01 Civ.1948(SAS). United States District Court, S.D. New York. (July 29, 2001)