Of Mice and Men is a 1992 American film starring John Malkovich and Gary Sinise, directed and produced by Sinise. It is the third movie adaptation of John Steinbeck's 1937 novel of the same name. The first adaptation was made in 1939, and a made-for-TV movie version was produced in 1981.

Plot

George Milton (Gary Sinise) is in a train boxcar, reminiscing upon the events that have just happened. He thinks back to when he and his companion Lennie Small (John Malkovich) are fleeing from their previous employment in Weed. They were run out of town after Lennie was accused of attempted rape when he touched a young woman's dress (prompted by his love of stroking soft things). Then George thinks of the events that have recently happened and make up the movie, taking place during the Great Depression. After running from Weed, George and Lennie are trying to attain their shared dream of settling down on their own piece of land. Lennie's part of the dream, which he never tires of hearing George describe, is merely to have soft rabbits on the farm, which he can pet. The two go to work at a ranch named Tyler Ranch.