Nutty Professor II: The Klumps is a 2000 comedy film directed by Peter Segal. The film is a sequel to the The Nutty Professor and stars Eddie Murphy and Janet Jackson. Murphy plays not only the inept but brilliant scientist, Sherman Klump, as in the first film, but also (wearing different, but equally elaborate makeup) most of Sherman's family as well. Various subplots involving his family occupy a substantial part of the film.

Just like the first film, the film's theme song is "Macho Man" by The Village People, which this time is played during the end credits.

Plot

As the film opens, Sherman is working on a new miracle formulandash this time, the fountain of youth. He is also preparing to marry a fellow scientist, Denise Gaines (Janet Jackson). Unfortunately, he has started suffering from personality lapses that are threatening to alienate his bride-to-be: against his will, he acts like the obnoxious, hypersexed Buddy Love of the first film. After a particularly unpleasant incident, Sherman goes to his lab to analyze his DNA and locates Buddy Love's DNA in an abnormal gene. He decides to use Denise's genetic research methods to isolate the gene and permanently extract Buddy Love's DNA from his own. His assistant, Jason, tries to stop him, warning him that he might damage his health or even lose his intelligence. Sherman disregards the warning and, alone in his lab late at night, extracts Buddy's DNA.