Jimmy Kimmel Live! is an American late-night talk show, created and hosted by Jimmy Kimmel and broadcast on ABC.

The nightly hour-long show made its debut on January 26, 2003, following Super Bowl XXXVII. Jimmy Kimmel Live! is produced by Jackhole Productions in association with ABC Studios (formerly Touchstone Television). The TV Guide Network used to rebroadcast the previous night's episodes at 7:00pm Eastern Time, but this has since been discontinued. Westwood One, through 2008 and most of 2009, carried radio highlights of the show under the name "Great Moments with Jimmy Kimmel," but these were dropped in September 2009 in favor of highlights from The Jay Leno Show.

Jimmy Kimmel Live! is no longer truly "live"; instead, it is taped at 7:00 pm Pacific Time on the day of broadcast (two hours before it reaches air on the East Coast), except in the event of reruns. On rare occasions, though, it airs a special live edition, usually after the Academy Awards ceremonies.