This is an article about the film. For the video game based on this movie, see G.I. Joe: The Rise of Cobra (video game).

G.I. Joe: The Rise of Cobra is a 2009 American live-action film adaptation of the G.I. Joe toy franchise, with particular inspiration on the comic book G.I. Joe: A Real American Hero. The film is directed by Stephen Sommers, produced by Lorenzo di Bonaventura and co-written by Stuart Beattie, based on a 1998 screenplay by John Paul Kay. G.I. Joe features an ensemble cast based on the various characters of the franchise. The story follows two American soldiers, Duke and Ripcord, who join the G.I. Joe Team after being attacked by MARS troops.

After leaked drafts of the script were criticized by fans, Larry Hama, writer of the comic, was hired as creative consultant and rewrites were made. Filming took place in Downey, California and Prague's Barrandov Studios, and six different companies handled the visual effects. The film was released from August 5, to November 5, 2009, worldwide, following an extensive marketing campaign focused on the Mid-American public. Despite receiving mixed to negative reviews the film opened at the top of the box office and grossed over $302 million worldwide by the end of its run. A sequel is being planned.